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There seems to be great promise of overcoming many eye and vision problems with the use of Stem Cells, Particularly Bone Marrow-derived Adult Stem Cells. Most of the techniques in the current scientific literature are invasive and will not be available for human use for some time.
A peer reviewed double blind Scientific study shows how you can naturally increase the number of your own circulating bone marrow-derived Adult stem cells by an average 25%. Look at the Non-Medical Alternatives section to find out more.
Kamla Dutt, Yang Cao.
Tissue Engineering Part A. June 2009, Volume: 15 Issue 6: July 10, 2009
Retinal degeneration resulting in the loss of photoreceptors is the leading cause of blindness. Several therapeutic protocols are under consideration for treatment of this disease. Tissue replacement is one such strategy currently being explored. However, availability of tissues for transplant poses a major obstacle. Another strategy with great potential is the use of adult stem cells, ......The capability of retinal progenitors to give rise to several retinal cell types when grown as aggregated cells in rotary culture offers hope that progenitor stem cells under appropriate culture conditions will be valuable to engineer retinal constructs, which could be further tested for their transplant potential. The fidelity with which this multipotential cell line retains its capacity to differentiate into multiple cell types holds great promise for the use of tissue-specific adult stem cells for therapy.
Atsushi Otani1, Michael Ian Dorrell1, Karen Kinder1, Stacey K. Moreno1, Steven Nusinowitz2, Eyal Banin1, John Heckenlively2 and Martin Friedlander1
Published in Volume 114, Issue 6 (September 15,2004) J. Clin. Invest. 114(6): 765-774 (2004). doi:10.1172/JCI21686. Copyright © 2004, American Society for Clinical Investigation Research Article
In part this study states....We now report that adult bone marrow-derived Lin- HSCs, when injected intravitreally up to 2 weeks postnatally, can completely prevent retinal vascular degeneration ordinarily observed in the rd1 or rd10 mouse models of retinal degeneration, and this vascular rescue correlates with neuronal rescue.....
Raymond D. Lund, Shaomei Wang, Irina Klimanskaya, Toby Holmes, Rebeca Ramos-Kelsey, Bin Lu, Sergej Girman, N. Bischoff, Yves Sauvé, Robert Lanza.
Cloning and Stem Cells. Fall 2006, 8(3): 189-199. doi:10.1089/clo.2006.8.189. Published in Volume: 8 Issue 3: September 29, 2006
Embryonic stem cells promise to provide a well-characterised and reproducible source of replacement tissue for human clinical studies. An early potential application of this technology is the use of retinal pigment epithelium (RPE) for the treatment of retinal degenerative diseases such as macular degeneration. Here we show the reproducible generation of RPE (67 passageable cultures established from 18 different hES cell lines); batches of RPE derived from NIH-approved hES cells (H9) were tested and shown capable of extensive photoreceptor rescue in an animal model of retinal disease, the Royal College of Surgeons (RCS) rat, in which photoreceptor loss is caused by a defect in the adjacent retinal pigment epithelium.
Improvement in visual performance was 100% over untreated controls (spatial acuity was approximately 70% that of normal nondystrophic rats) without evidence of untoward pathology.
Nilanjana Sengupta Sergio Caballero Robert N. Mames Jason M. Butler Edward W. Scott and Maria B. Grant
Investigative Ophthalmology and Visual Science. 2003;44:4908-4913.) © 2003
Age-related macular degeneration (ARMD) is the primary cause of blindness in people aged of 50 years or more. The wet form leads to severe loss of central vision. Recent evidence supports that adult hematopoietic stem cells (HSCs) contribute to pre-retinal neovascularization. In the current study, it was determined whether HSCs, by producing both blood and blood vessels, provide functional hemangioblast activity during choroidal neovascularization (CNV) in mice.
CONCLUSIONS. Adult stem cells are recruited to the choroid in a model of CNV, where they contribute to forming aberrant new vessels. This observation suggests that targeting stem cell recruitment to the eye may offer a novel therapeutic strategy for ARMD.
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