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Lucia Urdzíková, Pavla Jendelová, KateYina Glogarová, Martin Burian, Milan Hájek, Eva Syková. Journal of Neurotrauma. September 2006, 23(9): 1379-1391. doi:10.1089/neu.2006.23.1379. Published in Volume: 23 Issue 9: September 7, 2006
...We conclude that treatment with three different bone marrow cell populations had a positive effect on behavioural outcome and histopathological assessment after SCI, which was most pronounced after MSC injection.
R K W Smith, P M Webbon British Journal of Sports Medicine 2005;39:582-584
Stem cell technology may be useful in the treatment of tendon and ligament injuries
Strain induced tendon or ligament injuries are an all too common consequence of athletic endeavour in both horses and humans, resulting in high morbidity and often compromising a return to the same level of activity.
Edward J. Caterson, BS, Leon J. Nesti, PhD, Todd Albert, MD, Keith Danielson, PhD, Rocky Tuan, PhD, Department of Orthopaedic Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania Published: 02/05/2001 source: Medscape
...Clinically applicable techniques to isolate, expand, and re-implant these autogenous cells will become part of the repertoire of orthopaedic therapy. In the presence of extrinsic signalling molecules, provided by both the clinician and the local cellular environment, the intrinsic multipotential nature of the stem cells may be realised for applications such as the replacement of bone graft for segmental defects, nonunions, and spinal fusions. Additional applications may include treatment of full-thickness articular defects and articular resurfacing by site-specific delivery of stem cells. The ultimate goal is directed cellular regeneration of damaged or diseased musculoskeletal tissue. Currently, the limitation is our knowledge and ability to direct this differentiation, but with further study molecular orthopaedic interventions should become a reality.
S C Hayes, P S Davies, T W Parker, J Bashford, A Green British Journal of Sports Medicine 2004;38:304-309
Objectives: To evaluate the effect of peripheral blood stem cell transplantation on functional capacity, and to determine the role of a mixed type, moderate intensity exercise programme in the recovery of patients after intensive cancer treatment.
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