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An advantage of using adult stem cells is that in most cases the patient’s own stem cells can be used for the treatment, circumventing the problems of immune rejection, and without tumour formation. The mechanism for these amazing regenerative treatments is still unclear. Adult stem cells in some cases appear capable of inter-conversion between different tissue types, known as transdifferentiation. In some tissues, adult stem cells appear to fuse with the host tissue and take on that tissue’s characteristics, facilitating regeneration. And in some studies, the adult stem cells do not directly contribute to the regenerating tissue, but instead appear to stimulate the endogenous cells of the tissue to begin repair.
Whatever the mechanism, the adult cells are successful at regenerating damaged tissue. As Robert Lanza, a proponent of embryonic stem cells and cloning has noted, “there is ample scientific evidence that adult stem cells can be used to repair damaged heart or brain tissue… if it works, it works, regardless of the mechanism.”30 The citations given above for adult stem cells are only a sampling, including some more recent references. A representative list of diseases currently in patient trials with adult stem cells is given as Appendix A.
In summary, adult stem cells have been shown by the published evidence to be a more promising alternative for patient treatments, with a vast biomedical potential. Adult stem cells have proven success in the laboratory dish, in animal models of disease, and in current clinical treatments. Adult stem cells also avoid problems with tumour formation, transplant rejection, and provide realistic excitement for patient treatments.
David Prentice speaks in part of this YouTube Video
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